Ott covered emerging vaccine-style approaches using peptides, DNA and mRNA at a special symposium on melanoma.
Recap by typeshit. Post by Dana-Farber on X.
The once-daily pill blocks the IL-23 receptor and helped people with moderate to severe ulcerative colitis respond more often than placebo, a new study reports.
Bikman welcomes a new result but argues the likely cause is tirzepatide bringing insulin down rather than the drug slowing aging itself. His view, not a study claim.
Marchione makes the case for pairing GLP-1s with drugs that target amylin, the hormone released after meals that signals fullness to the brain.
Regen says the placebo group saw a 9% drop, while people on retatrutide also lost 31 lb on average and saw systolic blood pressure fall 14 points.
Healio
In Lilly's TOGETHER trials, the combo group lost about 16 to 18 kg by week 36 versus roughly 1 kg on Taltz alone, with better blood pressure and HbA1c.
Benjamin Bikman notes participants lost 12 to 22% of body weight on Lilly's triple agonist, and argues the drug works through weight loss rather than the airway itself.
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