Healio
In Lilly's TOGETHER trials, the combo group lost about 16 to 18 kg by week 36 versus roughly 1 kg on Taltz alone, with better blood pressure and HbA1c.
Recap by typeshit. Full story at Healio.
Avi Roy points out that the largest test so far found no memory benefit from the drug in Ozempic, despite hopes raised by health record studies.
Balwinder Singh and Raman Baweja link GLP-1 use to less kidney replacement therapy in bipolar patients with CKD, and flag lithium toxicity cases.
Yale Medicine says 5% to 10% of people on GLP-1 weight loss drugs see little result, and points to diet as one factor that can blunt the effect.
24:26
A doctor's explainer sorting peptides into eight broad categories. An evergreen overview for anyone still learning the basics.
Pannu points to over $8B in upfront FGF21 deals and 500+ assets in development, and says the commercial and clinical split is arriving unusually early.
Analysts led by Yang Huang expect about 15% yearly growth, citing the large diabetes and obesity burden across the three countries.
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