The rheumatologist points to NEJM results reporting up to 25% weight reduction on retatrutide, with subanalyses showing less knee osteoarthritis pain.
Recap by typeshit. Post by Dr. John Cush on X.
An explainer on how GLP-1 drugs act on reward and craving in the brain, and the research testing them against alcohol, nicotine and other substance use.
Dr Alo, a cardiologist, says he is following the cardiovascular data on these drugs closely and that it is shifting how heart disease is treated.
Robert Lufkin MD shares the observational data: an average 16.1 kg lost at six months among 7,297 women, with 62.7% reporting side effects.
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DOWNSIZED looks at why appetite and food noise can creep back late in the weekly cycle, and what that may say about whether a GLP-1 is still working.
He lists what Japanese clinics advertise BPC-157, TB-500 and Epitalon for, and notes the FDA has flagged missing human safety data for several of them.
A short general post notes the investigational triple agonist has shown strong trial results but can cause side effects. Thin on detail.
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