Designed enzymes that cut protein chains rely on zinc and a well placed water molecule beside the peptide. Leave that water out and AI design can go wrong.
Recap by typeshit. Post by Jorge Bravo Abad on X.
An explainer on how GLP-1 drugs act on reward and craving in the brain, and the research testing them against alcohol, nicotine and other substance use.
Dr Alo, a cardiologist, says he is following the cardiovascular data on these drugs closely and that it is shifting how heart disease is treated.
Robert Lufkin MD shares the observational data: an average 16.1 kg lost at six months among 7,297 women, with 62.7% reporting side effects.
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DOWNSIZED looks at why appetite and food noise can creep back late in the weekly cycle, and what that may say about whether a GLP-1 is still working.
Inc. reports the peptide could damage neurons in lab tests, though its role in people with Alzheimer's has not been shown.
Researchers reviewed posts from 13,589 users, with increased appetite and fatigue most common. Lilly says anyone selling retatrutide to consumers is breaking the law.
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