Lagakos posts a chart showing the amylin agonist eloralintide with tirzepatide reached about 25% weight loss, more than either drug on its own.
Recap by typeshit. Post by William Lagakos on X.
A Facebook share says Danish teams found certain bacterial strains may change how the gut tells the brain it is full. The work so far is in animal models only.
Bikman calls the results remarkable, but he argues that bigger drops make it more important to know how much of the lost weight is fat and how much is muscle.
Bikman points out that weight usually returns once the drug is stopped, which makes the question of lifelong use a real one.
Avi Roy flags a preprint that pooled 10,052 people from five semaglutide trials and used a blood test to estimate heart age. It has not yet been peer reviewed.
Answering doubters, she says her experience has been good and walks through upsides she didn't expect. She notes she is not a medical professional.
In a clip from their conversation, Dr Strumeier argues the scale can't show whether you're losing fat or muscle, and says keeping muscle should be part of the plan.
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