He points to GLP-1 receptors in dopamine pathways tied to cravings for food, alcohol and nicotine as the more interesting part of how the drugs work.
Recap by typeshit. Post by @bcrawforddc on Instagram.
An explainer on how GLP-1 drugs act on reward and craving in the brain, and the research testing them against alcohol, nicotine and other substance use.
Dr Alo, a cardiologist, says he is following the cardiovascular data on these drugs closely and that it is shifting how heart disease is treated.
Robert Lufkin MD shares the observational data: an average 16.1 kg lost at six months among 7,297 women, with 62.7% reporting side effects.
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DOWNSIZED looks at why appetite and food noise can creep back late in the weekly cycle, and what that may say about whether a GLP-1 is still working.
Jen Can NuSH argues that overlapping definitions explain why nausea and vomiting rates track so closely in reported side effect numbers.
AJMC has a video on heart failure care making the case that these two drug classes each have a separate role and can't simply be swapped for one another.
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